Name
Abstract | ||
|---|---|---|
Object: To assess the accuracy and reproducibility of semi-automatic vessel axis extraction and stenosis quantification in 3D contrast-enhanced Magnetic Resonance Angiography (CE-MRA) of the carotid arteries (CA).
Materials and methods: A total of 25 MRA datasets was used: 5 phantoms with known stenoses, and 20 patients (40 CAs) drawn from a multicenter trial database. Maracas software extracted vessel centerlines and quantified the stenoses, based on boundary detection in planes perpendicular to the centerline. Centerline accuracy was visually scored. Semi-automatic measurements were compared with: (1) theoretical phantom morphometric values, and (2) stenosis degrees evaluated by two independent radiologists.
Results: Exploitable centerlines were obtained in 97% of CA and in all phantoms. In phantoms, the software achieved a better agreement with theoretic stenosis degrees (weighted kappa κ
w
= 0.91) than the radiologists (κ
w
= 0.69). In patients, agreement between software and radiologists varied from κ
w
=0.67 to 0.90. In both, Maracas was substantially more reproducible than the readers. Mean operating time was within 1 min/ CA.
Conclusion: Maracas software generates accurate 3D centerlines of vascular segments with minimum user intervention. Semi-automatic quantification of CA stenosis is also accurate, except in very severe stenoses that cannot be segmented. It substantially reduces the inter-observer variability. |
Year | DOI | Venue |
|---|---|---|
2006 | 10.1007/s11548-006-0049-1 | Int. J. Computer Assisted Radiology and Surgery |
Keywords | Field | DocType |
vascular diseases · carotid artery stenosis · magnetic resonance angiography · three-dimensional image · computer assisted image processing,image processing | Reproducibility,Carotid arteries,Stenosis,Magnetic resonance angiography,Radiology,Medicine | Journal |
Volume | Issue | ISSN |
1 | 3 | 1861-6429 |
Citations | PageRank | References |
3 | 0.45 | 2 |
Authors | ||
7 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Marcela Hernández Hoyos | 1 | 228 | 15.91 |
| Jean-Michel Serfaty | 2 | 3 | 0.45 |
| Albinka Maghiar | 3 | 3 | 0.45 |
| Catherine Mansard | 4 | 3 | 0.45 |
| Maciej Orkisz | 5 | 315 | 24.14 |
| Isabelle E. Magnin | 6 | 540 | 64.87 |
| Philippe C. Douek | 7 | 3 | 0.45 |