Title
Immune epitope database analysis resource.
Abstract
The immune epitope database analysis resource (IEDB-AR: http://tools.iedb.org) is a collection of tools for prediction and analysis of molecular targets of T- and B-cell immune responses (i.e. epitopes). Since its last publication in the NAR webserver issue in 2008, a new generation of peptide:MHC binding and T-cell epitope predictive tools have been added. As validated by different labs and in the first international competition for predicting peptide:MHC-I binding, their predictive performances have improved considerably. In addition, a new B-cell epitope prediction tool was added, and the homology mapping tool was updated to enable mapping of discontinuous epitopes onto 3D structures. Furthermore, to serve a wider range of users, the number of ways in which IEDB-AR can be accessed has been expanded. Specifically, the predictive tools can be programmatically accessed using a web interface and can also be downloaded as software packages.
Year
DOI
Venue
2012
10.1093/nar/gks438
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
peptide,computer applications,immune response,mhc i,computational biology,immune system
Epitope,Biology,Major histocompatibility complex,Software,Immune system,User interface,Molecular biology,Database analysis,The Internet,Web server
Journal
Volume
Issue
ISSN
40
W1
0305-1048
Citations 
PageRank 
References 
11
0.99
12
Authors
12
Name
Order
Citations
PageRank
Yohan Kim1110.99
Julia V. Ponomarenko225724.02
Zhanyang Zhu3272.40
Dorjee Tamang4110.99
Peng Wang5272.74
Jason Greenbaum6837.42
Claus Lundegaard736527.39
Alessandro Sette862242.54
Ole Lund952744.47
Philip E. Bourne101995388.17
Morten Nielsen1146931.89
Bjoern Peters1261044.67