Paper Info
Title
Quantification of opioid receptor availability following spontaneous epileptic seizures: Correction of [11C]diprenorphine PET data for the partial-volume effect.
Abstract
Previous positron emission tomography (PET) studies in refractory temporal lobe epilepsy (TLE) using the non-selective opioid receptor antagonist [11C]diprenorphine (DPN) did not detect any changes in mesial temporal structures, despite known involvement of the hippocampus in seizure generation. Normal binding in smaller hippocampi is suggestive of increased receptor concentration in the remaining grey matter. Correction for partial-volume effect (PVE) has not been used in previous DPN PET studies. Here, we present PVE-corrected DPN-PET data quantifying post-ictal and interictal opioid receptor availability in humans with mTLE.
Year
DOI
Venue
2013
10.1016/j.neuroimage.2013.04.015
NeuroImage
Keywords
Field
DocType
[11C]DPN,DOP,KOP,HS,MAPER,MOP,MR,OPR,PVE,SFS-RR,TLE,VT
Nuclear medicine,Opioid receptor,Psychology,Epilepsy,Diprenorphine,Parahippocampal gyrus,Hippocampus,Hippocampal sclerosis,Ictal,Temporal lobe
Journal
Volume
ISSN
Citations 
79
1053-8119
0
PageRank 
References 
Authors
0.34
6
12
Name
Order
Citations
PageRank
Colm J. McGinnity142.27
Miho Shidahara2143.24
Maria Feldmann301.35
Shiva Keihaninejad418411.38
Daniela A. Riaño Barros551.94
Ioannis S. Gousias61248.13
J S Duncan736838.49
David J. Brooks8247.54
Rolf A. Heckemann969743.14
Federico E. Turkheimer105711.41
Alexander Hammers1193561.73
M Koepp12757.40