Paper Info
Title
Information Criteria for Dynamic Contrast-Enhanced Magnetic Resonance Imaging.
Abstract
Inflammatory lesions form in the brain and spinal cord of patients with multiple sclerosis (MS). In many active MS lesions, blood flows abnormally into the white matter of the brain due to breakdown of the blood-brain barrier (BBB), which is know to be associated with morbidity and disability. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) allows quantitative study of blood flow and permeability dynamics throughout the brain. In our study, we observe 15 patients who undergo DCE-MRI periodically throughout a year. In this paper, we design and study spatiotemporal parameters of interest that cannot be obtained by visual inspection. Examples of such parameters are the rate and maximum intensity observed in regions of interest. We develop semi parametric methods for this quantification of BBB disruption at each visit.
Year
DOI
Venue
2013
10.1109/PRNI.2013.19
Pattern Recognition in Neuroimaging
Keywords
Field
DocType
active ms lesion,blood flow,multiple sclerosis,study spatiotemporal parameter,dynamic contrast-enhanced magnetic resonance,quantitative study,inflammatory lesions form,magnetic resonance imaging,bbb disruption,blood-brain barrier,maximum intensity,information criteria,time series analysis,visual inspection,dynamic contrast enhanced mri,haemodynamics,permeability
Hemodynamics,Spinal cord,Contrast-enhanced Magnetic Resonance Imaging,Blood flow,White matter,Multiple sclerosis,Dynamic contrast-enhanced MRI,Nuclear magnetic resonance,Medicine,Pathology,Magnetic resonance imaging
Conference
ISSN
Citations 
PageRank 
2330-9989
0
0.34
References 
Authors
3
4
Name
Order
Citations
PageRank
Russell T. Shinohara1161.62
Ciprian S. Crainiceanu200.34
Brian S. Caffo31347.65
Daniel S. Reich420915.94