Title
The human (PEDB) and mouse (mPEDB) Prostate Expression Databases.
Abstract
The Prostate Expression Databases (PEDB and mPEDB) are online resources designed to allow researchers to access and analyze gene expression information derived from the human and murine prostate, respectively. Human PEDB archives more than 84 000 Expressed Sequence Tags (ESTs) from 38 prostate cDNA libraries in a curated relational database that provides detailed library information including tissue source, library construction methods, sequence diversity and sequence abundance. The differential expression of each EST species can be viewed across all libraries using a Virtual Expression Analysis Tool (VEAT), a graphical user interface written in Java for intra- and inter-library sequence comparisons. Recent enhancements to PEDB include (i) the development of a murine prostate expression database, mPEDB, that complements the human gene expression information in PEDB, (ii) the assembly of a non-redundant sequence set or 'prostate unigene' that represents the diversity of gene expression in the prostate, and (iii) an expanded search tool that supports both text-based and BLAST queries. PEDB and mPEDB are accessible via the World Wide Web at http://www.pedb.org and http://www.mpedb.org.
Year
DOI
Venue
2002
10.1093/nar/30.1.218
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
graphic user interface,expressed sequence tags,internet,world wide web,expressed sequence tag,cdna library,forecasting,gene expression,database management systems,relational database
Differential expression,Expressed sequence tag,Relational database,Biology,Expression analysis,UniGene,Prostate,cDNA library,Basic Local Alignment Search Tool,Database
Journal
Volume
Issue
ISSN
30
1
0305-1048
Citations 
PageRank 
References 
1
0.72
1
Authors
4
Name
Order
Citations
PageRank
Peter S. Nelson1174.18
Colin C. Pritchard281.92
Denise Abbott310.72
Nigel Clegg411.06