Title
Intermodality Nonrigid Breast-Image Registration
Abstract
We investigated nonrigid co-registration of PET and MR breast images to improve diagnostic specificity in difficult-to-interpret mammograms, and ultimately to avoid biopsy. A deformable breast model based on a finite-element method (FEM) was employed. The FEM "loads" were taken as the observed intermodal displacements of several fiducial skin markers placed on the breast and visible in PET and MRI. The analogy between orthogonal components of the displacement field and the temperature differences in a steady-state heat transfer (SSHT) in solids was adopted. The model allows estimation of the intermodal breast deformation for every location within the breast. To test our model, an elastic breast phantom with simulated internal "lesions" and external markers was imaged with PET and MRI. We estimated fiducial- and target-registration errors vs. number and location of the fiducials. We established that SSHT approach using external fiducial markers is accurate to within ~5 mm.
Year
DOI
Venue
2004
10.1109/ISBI.2004.1398819
ISBI
Keywords
Field
DocType
solids,skin,displacement field,finite element methods,finite element method,steady state,cancer,image registration,magnetic resonance imaging,temperature,heat transfer,gynaecology,finite element analysis,fem
Nuclear medicine,Displacement field,Fiducial marker,Diagnostic Specificity,Computer science,Imaging phantom,Positron emission tomography,Image registration,Breast deformation
Conference
Citations 
PageRank 
References 
2
0.57
0
Authors
8
Name
Order
Citations
PageRank
Ioana L. Coman1377.28
Andrzej Król2184.99
David H. Feiglin3188.32
Wei Li439676.68
Edward Lipson562.56
James A. Mandel663.54
Karl G. Baum7134.71
Mehmet Z. Unlu863.20