Name
Title | ||
|---|---|---|
EasyMIFS and SiteHound: a toolkit for the identification of ligand-binding sites in protein structures. |
Abstract | ||
|---|---|---|
SITEHOUND uses Molecular Interaction Fields (MIFs) produced by EASYMIFS to identify protein structure regions that show a high propensity for interaction with ligands. The type of binding site identified depends on the probe atom used in the MIF calculation. The input to EASYMIFS is a PDB. le of a protein structure; the output MIF serves as input to SITEHOUND, which in turn produces a list of putative binding sites. Extensive testing of SITEHOUND for the detection of binding sites for drug-like molecules and phosphorylated ligands has been carried out. |
Year | DOI | Venue |
|---|---|---|
2009 | 10.1093/bioinformatics/btp562 | BIOINFORMATICS |
Keywords | DocType | Volume |
binding sites,computational biology,protein structure,ligand binding,proteins,ligands | Journal | 25 |
Issue | ISSN | Citations |
23 | 1367-4803 | 11 |
PageRank | References | Authors |
0.67 | 7 | 2 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Dario Ghersi | 1 | 66 | 7.04 |
| Roberto Sanchez | 2 | 50 | 4.68 |