Paper Info
Title
Flytf: Improved Annotation And Enhanced Functionality Of The Drosophila Transcription Factor Database
Abstract
FlyTF (http://www.flytf.org) is a database of computationally predicted and/or experimentally verified site-specific transcription factors (TFs) in the fruit fly Drosophila melanogaster. The manual classification of TFs in the initial version of FlyTF that concentrated primarily on the DNA-binding characteristics of the proteins has now been extended to a more fine-grained annotation of both DNA binding and regulatory properties in the new release. Furthermore, experimental evidence from the literature was classified into a defined vocabulary, and in collaboration with FlyBase, translated into Gene Ontology (GO) annotation. While our GO annotations will also be available through FlyBase as they will be incorporated into the genes' official GO annotation in the future, the entire evidence used for classification including computational predictions and quotes from the literature can be accessed through FlyTF. The FlyTF website now builds upon the InterMine framework, which provides experimental and computational biologists with powerful search and filter functionality, list management tools and access to genomic information associated with the TFs.
Year
DOI
Venue
2010
10.1093/nar/gkp910
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
transcription factors,dna,internet,computational biology
Genome,Drosophila Protein,Annotation,Biology,Gene ontology,Drosophila melanogaster,FlyBase : A Database of Drosophila Genes & Genomes,Genetics,Vocabulary,Transcription factor,Database
Journal
Volume
Issue
ISSN
38
Database issue
0305-1048
Citations 
PageRank 
References 
8
1.27
5
Authors
6
Name
Order
Citations
PageRank
Ulrike Pfreundt181.27
Daniel P James281.27
Tweedie Susan31409.50
Derek Wilson448550.74
Sarah A Teichmann523922.64
Boris Adryan6786.46