Abstract | ||
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We formalize the notion of a DNA hairpin secondary structure, examining its mathematical properties. Two related secondary structures are also investigated, taking into the account imperfect bonds (bulges, mismatches) and multiple hairpins. We characterize maximal sets of hairpin-forming DNA sequences, as well as hairpin-free ones. We study their algebraic properties and their computational complexity. Related polynomial-time algorithms deciding hairpin-freedom of regular sets are presented. Finally, effective methods for design of long hairpin-free DNA words are given. |
Year | DOI | Venue |
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2005 | 10.1007/11753681_12 | DNA |
Keywords | Field | DocType |
account imperfect bond,hairpin structure,mathematical property,algebraic property,long hairpin-free dna word,related secondary structure,effective method,hairpin-forming dna sequence,related polynomial-time,computational complexity,dna hairpin secondary structure,dna sequence,secondary structure | Algorithm,DNA,Pushdown automaton,DNA sequencing,Regular language,Algebraic properties,Protein secondary structure,A-DNA,Mathematics,Computational complexity theory | Conference |
Volume | ISSN | ISBN |
3892 | 0302-9743 | 3-540-34161-7 |
Citations | PageRank | References |
17 | 1.07 | 11 |
Authors | ||
5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Lila Kari | 1 | 1123 | 124.45 |
Stavros Konstantinidis | 2 | 283 | 31.10 |
Elena Losseva | 3 | 44 | 3.48 |
Petr Sosík | 4 | 479 | 68.66 |
Gabriel Thierrin | 5 | 263 | 34.89 |