Paper Info
Title
Improved Regional Analysis of Oxygen-Enhanced Lung MR Imaging Using Image Registration
Abstract
Oxygen enhanced MR imaging of the lung is a promising technique for monitoring a range of pulmonary diseases but regional analysis is hampered by lung motion and volume changes due to breathing. We have developed an image registration method to improve the quantitative regional analysis of both static and dynamic oxygen-enhanced pulmonary MRI. Images were acquired using a HASTE sequence at 1.5T for five normal volunteers alternately breathing air and 100% oxygen. Static images were used to calculate regional changes in relaxation rate between breathing air and oxygen which is directly related to the increase in the dissolved oxygen concentration. Dynamic scans were used to calculate regional maps of oxygen wash-in and wash-out time constants. The method provided significant improvements in the both the static and the dynamic analysis. This may provide improved information in the regional assessment of chronic obstructive lung diseases.
Year
DOI
Venue
2004
10.1007/978-3-540-30135-6_105
Lecture Notes in Computer Science
Keywords
Field
DocType
time constant,dynamic analysis,dissolved oxygen,image registration
Mr imaging,Nuclear medicine,Active shape model,Lung,Breathing gas,Oxygen,Oxygen saturation,Breathing,Medicine,Image registration
Conference
Volume
ISSN
Citations 
3216
0302-9743
0
PageRank 
References 
Authors
0.34
3
7
Name
Order
Citations
PageRank
Josephine H. Naish142.06
Geoffrey J. M. Parker244439.62
Paul C. Beatty300.34
Alan Jackson4122.44
John C. Waterton515314.44
Simon S. Young600.34
Christopher J. Taylor75140819.69