Title
Transcription-associated protein families are primarily taxon-specific.
Abstract
The mechanisms controlling gene regulation appear to be fundamentally different in eukaryotes and prokaryotes (Struhl (1999) Cell, 98, 1-4). To investigate this diversity further, we have analysed the distribution of all known transcription-associated proteins (TAPs), as reflected by sequence database annotations. Our results for the primary phylogenetic domains (Archaea, Bacteria and Eukaryota) show that TAP families are mostly taxon-specific and very few transcriptional regulators are common across these domains.
Year
DOI
Venue
2001
10.1093/bioinformatics/17.1.95
BIOINFORMATICS
Keywords
Field
DocType
protein family
Sequence alignment,Protein family,Archaea,Sequence database,Phylogenetic tree,Biology,Genomics,Regulation of gene expression,Homology (biology),Bioinformatics,Genetics
Journal
Volume
Issue
ISSN
17
1
1367-4803
Citations 
PageRank 
References 
5
3.03
1
Authors
3
Name
Order
Citations
PageRank
Richard M. R. Coulson1174.40
Anton J. Enright277886.87
Christos A. Ouzounis3879200.77