Abstract | ||
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The mechanisms controlling gene regulation appear to be fundamentally different in eukaryotes and prokaryotes (Struhl (1999) Cell, 98, 1-4). To investigate this diversity further, we have analysed the distribution of all known transcription-associated proteins (TAPs), as reflected by sequence database annotations. Our results for the primary phylogenetic domains (Archaea, Bacteria and Eukaryota) show that TAP families are mostly taxon-specific and very few transcriptional regulators are common across these domains. |
Year | DOI | Venue |
---|---|---|
2001 | 10.1093/bioinformatics/17.1.95 | BIOINFORMATICS |
Keywords | Field | DocType |
protein family | Sequence alignment,Protein family,Archaea,Sequence database,Phylogenetic tree,Biology,Genomics,Regulation of gene expression,Homology (biology),Bioinformatics,Genetics | Journal |
Volume | Issue | ISSN |
17 | 1 | 1367-4803 |
Citations | PageRank | References |
5 | 3.03 | 1 |
Authors | ||
3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Richard M. R. Coulson | 1 | 17 | 4.40 |
Anton J. Enright | 2 | 778 | 86.87 |
Christos A. Ouzounis | 3 | 879 | 200.77 |