Name
Title | ||
|---|---|---|
zCall: a rare variant caller for array-based genotyping: Genetics and population analysis. |
Abstract | ||
|---|---|---|
zCall is a variant caller specifically designed for calling rare single-nucleotide polymorphisms from array-based technology. This caller is implemented as a post-processing step after a default calling algorithm has been applied. The algorithm uses the intensity profile of the common allele homozygote cluster to define the location of the other two genotype clusters. We demonstrate improved detection of rare alleles when applying zCall to samples that have both Illumina Infinium HumanExome BeadChip and exome sequencing data available. |
Year | DOI | Venue |
|---|---|---|
2012 | 10.1093/bioinformatics/bts479 | BIOINFORMATICS |
Keywords | Field | DocType |
exome,alleles,cluster analysis,algorithms | Genotype,Data mining,Genotyping,Exome,Computer science,Bioinformatics,Exome sequencing,Genotyping Techniques | Journal |
Volume | Issue | ISSN |
28 | 19 | 1367-4803 |
Citations | PageRank | References |
2 | 0.43 | 1 |
Authors | ||
17 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Jacqueline I. Goldstein | 1 | 2 | 0.43 |
| Andrew Crenshaw | 2 | 17 | 3.01 |
| Jason Carey | 3 | 2 | 0.43 |
| George B. Grant | 4 | 2 | 0.43 |
| Jared Maguire | 5 | 2 | 0.43 |
| Menachem Fromer | 6 | 143 | 10.47 |
| Colm O'Dushlaine | 7 | 8 | 1.96 |
| Jennifer L. Moran | 8 | 2 | 0.43 |
| Kimberly Chambert | 9 | 2 | 0.43 |
| Christine Stevens | 10 | 2 | 0.77 |
| Pamela Sklar | 11 | 2 | 0.43 |
| Christina M Hultman | 12 | 8 | 1.17 |
| S Purcell | 13 | 43 | 7.47 |
| Steven A. McCarroll | 14 | 2 | 0.77 |
| patrick f sullivan | 15 | 165 | 22.87 |
| Mark Daly | 16 | 190 | 33.59 |
| Benjamin M. Neale | 17 | 3 | 1.12 |