Title
Brownian motion, fluctuation and life.
Abstract
The measurements of dynamic behaviors of biomolecules in relation to their functions have been allowed using single molecule measurements. Thermal Brownian motion causes random step motion of motor proteins and structural fluctuation of protein molecules between multiple states. In hierarchic structure of life, the fluctuation is modulated. Random fluctuation is biased to directional motion and reactions as a result of interaction of proteins. The fluctuation of kinetic state of signaling proteins results in polarization and localization of cells. A recognition process in brain is also explained by the equation analogous to biochemical reaction at the molecular level. Thus dynamic processes originated from thermal motion may play an important role in activation processes in life.
Year
DOI
Venue
2007
10.1016/j.biosystems.2006.08.012
Biosystems
Keywords
Field
DocType
Fluctuation, Brownian motion, Single molecule measurement, Molecular motor, Cell signaling process, Dynamic structure of protein, Recognition in brain
Physical chemistry,Biology,Molecular motor,Molecule,Polarization (waves),Artificial intelligence,Kinetic energy,Statistical physics,Biomolecule,Thermal,Brownian motion,Machine learning,Motor protein
Journal
Volume
Issue
ISSN
88
3
0303-2647
Citations 
PageRank 
References 
12
1.46
0
Authors
5
Name
Order
Citations
PageRank
Toshio Yanagida110230.93
Masahiro Ueda2276.49
Tsutomu Murata3162.60
Seiji Esaki4163.00
Yoshiharu Ishii5174.46