Title
Visualization of Cat Auditory Cortical Functional Organization after Electrical Stimulation with a Multi-Channel Cochlear Implant by Means of Optical Imaging
Abstract
In order to study the effects of acute electrical cochlear stimulation on the topography of the cat auditory cortex, we measured reflectance changes by means of optical imaging of intrinsic signals. Following single pulse electrical stimulation at selected sites of a multichannel implant device, we found topographically restricted response areas. Systematic variation of the stimulation pairs and thus of the cochlear frequency sites revealed a systematic and corresponding shift of the response areas. Increasingly higher stimulation currents evoked increasingly larger response areas resulting in decreasing spatial, i.e. cochleotopic selectivity. The results indicate that optical imaging intrinsic signals is useful to visualize effects of cochlear stimulation, which results in a profound cochleotopic selectivity. The implications of these findings are discussed in respect to underlying mechanisms of sound sensation mediated by cochlear implants.
Year
DOI
Venue
1996
10.1007/BFb0046989
VBC
Keywords
Field
DocType
Optical Imaging,Cat Auditory Cortical Functional,Electrical Stimulation,Multi-Channel Cochlear Implant
Auditory cortex,Neuroprosthetics,Neuroscience,Visualization,Pulse (signal processing),Cochlear implant,Round window,Materials science,Sensation,Stimulation
Conference
Volume
ISSN
ISBN
1131
0302-9743
3-540-61649-7
Citations 
PageRank 
References 
0
0.34
1
Authors
7
Name
Order
Citations
PageRank
Hubert R. Dinse15711.83
Ben Godde263.24
Thomas Hilger310.70
G. Reuter400.34
S. M. Cords500.34
T. Lenarz600.34
W von Seelen7503140.13