Title
Syntactic approach to predict membrane spanning regions of transmembrane proteins
Abstract
This paper exploits “biological grammar” of transmembrane proteins to predict their membrane spanning regions using hidden Markov models and elaborates a set of syntactic rules to model the distinct features of transmembrane proteins. This paves the way to identify the characteristics of membrane proteins analogous to the way that identifies language contents of speech utterances by using hidden Markov models. The proposed method correctly predicts 95.24% of the membrane spanning regions of the known transmembrane proteins and correctly predicts 79.87% of the membrane spanning regions of the unknown transmembrane proteins on a benchmark dataset.
Year
DOI
Venue
2005
10.1007/978-3-540-32003-6_10
EvoWorkshops
Keywords
Field
DocType
transmembrane protein,syntactic approach,biological grammar,hidden markov model,unknown transmembrane protein,paper exploit,language content,benchmark dataset,membrane protein,known transmembrane protein,distinct feature
Discrete mathematics,Membrane protein,Membrane topology,Computer science,Membrane,Transmembrane protein,Artificial intelligence,Computational biology,Hidden Markov model,Syntax,Machine learning
Conference
Volume
ISSN
ISBN
3449
0302-9743
3-540-25396-3
Citations 
PageRank 
References 
0
0.34
5
Authors
2
Name
Order
Citations
PageRank
Koliya Pulasinghe1182.23
Jagath C. Rajapakse274783.00