Title
DockPro: a VR-based tool for protein-protein docking problem
Abstract
Proteins are large molecules that are vital for all living organisms and they are essential components of many industrial products. The process of binding a protein to another is called protein-protein docking. Many automated algorithms have been proposed to find docking configurations that might yield promising protein-protein complexes. However, these automated methods are likely to come up with false positives and have high computational costs. Consequently, Virtual Reality has been used to take advantage of user's experience on the problem; and proposed applications can be further improved. Haptic devices have been used for molecular docking problems; but they are inappropriate for protein-protein docking due to their workspace limitations. Instead of haptic rendering of forces, we provide a novel visual feedback for simulating physicochemical forces of proteins. We propose an interactive 3D application, DockPro, which enables domain experts to come up with dockings of protein-protein couples by using magnetic trackers and gloves in front of a large display.
Year
DOI
Venue
2008
10.1145/1477862.1477877
International Journal of Virtual Reality
Keywords
Field
DocType
promising protein-protein complex,docking configuration,vr-based tool,haptic rendering,automated algorithm,automated method,large display,haptic device,molecular docking problem,protein-protein docking,protein-protein docking problem,protein-protein couple,molecular docking,virtual reality,protein complex,industrial production,false positive
Computer vision,BitTorrent tracker,Docking (molecular),Virtual reality,Workspace,Simulation,Docking (dog),Computer science,Protein protein,Artificial intelligence,Haptic technology,False positive paradox
Conference
Volume
Issue
Citations 
08
2
0
PageRank 
References 
Authors
0.34
7
4
Name
Order
Citations
PageRank
Serdar Cakici100.34
Selcuk Sumengen251.78
Ugur Sezerman302.03
Selim Balcisoy426437.15