Title
TOM: enhancement and extension of a tool suite for in silico approaches to multigenic hereditary disorders.
Abstract
The study of complex hereditary diseases is a very challenging area of research. The expanding set of in silico approaches offers a flourishing ground for the acceleration of meaningful findings in this area by exploitation of rich and diverse sources of omic data. These approaches are cheap, flexible, extensible, often complementary and can continuously integrate new information and tests to improve the selection of genes responsible for hereditary diseases. Following this principle, we improved and extended our web-service TOM for the identification of candidate genes in the study of complex hereditary diseases.
Year
DOI
Venue
2008
10.1093/bioinformatics/btm588
BIOINFORMATICS
Keywords
Field
DocType
web pages,candidate gene,web service
Hereditary Diseases,Data mining,World Wide Web,Web page,Suite,Computer science,Bioinformatics,Hereditary disorders,In silico
Journal
Volume
Issue
ISSN
24
3
1367-4803
Citations 
PageRank 
References 
8
0.67
6
Authors
7
Name
Order
Citations
PageRank
Daniele Masotti1273.86
Christine Nardini2659.00
Simona Rossi3382.78
Elena Bonora4252.36
Giovanni Romeo5252.69
Stefano Volinia69418.64
Luca Benini7131161188.49