Abstract | ||
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A contact map is a key factor representing a specific protein structure. To simplify the protein contact map prediction, we predict the inter-residue contact clusters centred at the groups of their surrounding inter-residue contacts. In this paper, we adopt a Support Vector Machine (SVM)-based approach to predict the inter-residue contact cluster centres. The input of the SVM predictor includes sequence profile, evolutionary rate and predicted secondary structure. The SVM predictor is based on hydrophobic cores that may be considered as locations of the inter-residue contact clusters. About 35% of clustering centres of inter-residue contacts can be predicted accurately. |
Year | DOI | Venue |
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2008 | 10.1504/IJDMB.2010.037549 | IJDMB |
Keywords | DocType | Volume |
hydrophobic core,surrounding inter-residue contact,Support Vector Machine,contact map,protein contact map prediction,inter-residue contact,inter-residue contact cluster,secondary structure,inter-residue contact cluster centre,SVM predictor,specific protein structure | Conference | 4 |
Issue | ISSN | ISBN |
6 | 1748-5673 | 978-0-7695-3495-4 |
Citations | PageRank | References |
5 | 0.47 | 13 |
Authors | ||
6 |
Name | Order | Citations | PageRank |
---|---|---|---|
Peng Chen | 1 | 17 | 5.63 |
Chun-Mei Liu | 2 | 245 | 41.30 |
Legand Burge | 3 | 29 | 9.60 |
Mahmood Mohammad | 4 | 5 | 0.81 |
William Southerland | 5 | 15 | 6.23 |
Clay Gloster | 6 | 86 | 25.86 |