Title
A graphical representation for biological processes in the stochastic pi-calculus
Abstract
This paper presents a graphical representation for the stochastic π-calculus, which is formalised by defining a corresponding graphical calculus. The graphical calculus is shown to be reduction equivalent to stochastic π, ensuring that the two calculi have the same expressive power. The graphical representation is used to model a couple of example biological systems, namely a bistable gene network and a mapk signalling cascade. One of the benefits of the representation is its ability to highlight the existence of cycles, which are a key feature of biological systems. Another benefit is its ability to animate interactions between system components, in order to visualise system dynamics. The graphical representation can also be used as a front end to a simulator for the stochastic π-calculus, to help make modelling and simulation of biological systems more accessible to non computer scientists.
Year
DOI
Venue
2006
10.1007/11905455_7
T. Comp. Sys. Biology
Keywords
Field
DocType
biological process,example biological system,graphical representation,graphical calculus,corresponding graphical calculus,system dynamic,expressive power,bistable gene network,biological system,stochastic pi-calculus,computer scientist,system component,system dynamics,front end,gene network,biological systems
Front and back ends,Bistability,Chemical equation,Computer science,Pi calculus,Theoretical computer science,Artificial intelligence,Cascade,System dynamics,Gene regulatory network,Expressive power,Machine learning
Journal
Volume
ISSN
ISBN
4230
0302-9743
3-540-48837-5
Citations 
PageRank 
References 
30
2.02
9
Authors
3
Name
Order
Citations
PageRank
Andrew Phillips122717.50
Luca Cardelli262211002.41
Giuseppe Castagna31270128.82