Title
Blood flow simulation for the liver after a virtual right lobe hepatectomy.
Abstract
In this paper we present a hybrid 0D-3D modeling method to investigate the hepatic flow in a virtual right lobe hepatectomy (RLH), the surgical procedure for adult-to-adult living donor liver transplanation (LDLT). The 3D method is employed to simulate complex 3D flow in the portal vein, and the 0D model is used to study the systemic hepatic circulation. In particular, we quantify the flow velocity and wall shear stress (WSS) in the left portal vein which increase dramatically post-RLH, and also simulate the essential hepatic distribution features in a healthy adult pre- and post-procedure. We further predict the arterial flow in the remnant left liver, which would decrease due to a hepatic arterial buffer response (HABR) effect. Finally we discuss the physiological significance of these phenomena, and the potential of this hybrid modeling approach.
Year
DOI
Venue
2012
10.1007/978-3-642-33454-2_65
Lecture Notes in Computer Science
Field
DocType
Volume
Splenic vein,Computer science,Artificial intelligence,Flow velocity,Left portal vein,Superior mesenteric vein,Portal vein,Blood flow,Pattern recognition,Internal medicine,Lobe,Cardiology,Hepatectomy,General surgery
Conference
7512
Issue
ISSN
Citations 
Pt 3
0302-9743
1
PageRank 
References 
Authors
0.68
1
4
Name
Order
Citations
PageRank
Harvey Ho1186.75
Keagan Sorrell241.08
Adam Bartlett332.27
Hunter P J41352177.64