Title
Digital logic with molecular reactions
Abstract
This paper presents a methodology for implementing digital logic with molecular reactions based on a bistable mechanism for representing bits. The value of a bit is not determined by the concentration of a single molecular type; rather, it is the comparison of the concentrations of two complementary types that determines if the bit is "0" or "1". This mechanism is robust: any small perturbation or leakage in the concentrations quickly gets cleared out and the signal value is not affected. Based on this representation for bits, a constituent set of logical components are implemented. These include combinational components -- AND, OR, NOR, and XOR -- as well as sequential components -- D latches and D flip-flops. Using these components, three full-fledged design examples are given: a square-root unit, a binary adder and a linear feedback shift register. DNA-based computation via strand displacement is the target experimental chassis. The designs are validated through simulations of the chemical kinetics. The simulations show that the molecular systems compute digital functions accurately and robustly.
Year
DOI
Venue
2013
10.1109/ICCAD.2013.6691194
ICCAD
Keywords
Field
DocType
digital function,logic circuits,combinational circuits,combinational components,molecular reaction,circuit feedback,bistable mechanism,shift registers,d flip-flops,molecular system,logical components,d latches,dna-based computation,flip-flops,signal value,d flip-flop,single molecular type,molecular reactions,dna,linear feedback shift register,binary adder,digital logic,dilution,sample preparation,biochip
Digital electronics,Shift register,Logic gate,Sequential logic,Adder,Computer science,Algorithm,Electronic engineering,Combinational logic,Boolean algebra,Register-transfer level
Conference
ISSN
ISBN
Citations 
1092-3152
978-1-4799-1069-4
3
PageRank 
References 
Authors
0.51
8
3
Name
Order
Citations
PageRank
Hua Jiang1435.05
Marc D. Riedel252148.65
keshab k parhi33235369.07