Title
GND-PCA-based statistical modeling of diaphragm motion extracted from 4D MRI.
Abstract
We analyzed a statistical model of diaphragm motion using regular principal component analysis (PCA) and generalized N-dimensional PCA (GND-PCA). First, we generate 4D MRI of respiratory motion from 2D MRI using an intersection profile method. We then extract semiautomatically the diaphragm boundary from the 4D-MRI to get subject-specific diaphragm motion. In order to build a general statistical model of diaphragm motion, we normalize the diaphragm motion in time and spatial domains and evaluate the diaphragm motion model of 10 healthy subjects by applying regular PCA and GND-PCA. We also validate the results using the leave-one-out method. The results show that the first three principal components of regular PCA contain more than 98% of the total variation of diaphragm motion. However, validation using leave-one-out method gives up to 5.0mm mean of error for right diaphragm motion and 3.8mm mean of error for left diaphragm motion. Model analysis using GND-PCA provides about 1mm margin of error and is able to reconstruct the diaphragm model by fewer samples.
Year
DOI
Venue
2013
10.1155/2013/482941
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
Keywords
Field
DocType
movement,magnetic resonance imaging,diaphragm,respiratory mechanics,computer simulation,young adult,computational biology,principal component analysis
Computer vision,Diaphragm (structural system),Normalization (statistics),Respiratory motion,Computer science,Artificial intelligence,Statistical model,Margin of error,Principal component analysis
Journal
Volume
ISSN
Citations 
2013
1748-670X
0
PageRank 
References 
Authors
0.34
7
6
Name
Order
Citations
PageRank
Windra Swastika100.68
Yoshitada Masuda211.07
Rui Xu3234.30
Shoji Kido45316.61
Yen-Wei Chen5720155.73
Hideaki Haneishi615639.40