Title
CellFinder: a cell data repository.
Abstract
CellFinder (http://www.cellfinder.org) is a comprehensive one-stop resource for molecular data characterizing mammalian cells in different tissues and in different development stages. It is built from carefully selected data sets stemming from other curated databases and the biomedical literature. To date, CellFinder describes 3394 cell types and 50 951 cell lines. The database currently contains 3055 microscopic and anatomical images, 205 whole-genome expression profiles of 194 cell/tissue types from RNA-seq and microarrays and 553 905 protein expressions for 535 cells/tissues. Text mining of a corpus of >2000 publications followed by manual curation confirmed expression information on similar to 900 proteins and genes. CellFinder's data model is capable to seamlessly represent entities from single cells to the organ level, to incorporate mappings between homologous entities in different species and to describe processes of cell development and differentiation. Its ontological backbone currently consists of 204 741 ontology terms incorporated from 10 different ontologies unified under the novel CELDA ontology. CellFinder's web portal allows searching, browsing and comparing the stored data, interactive construction of developmental trees and navigating the partonomic hierarchy of cells and tissues through a unique body browser designed for life scientists and clinicians.
Year
DOI
Venue
2014
10.1093/nar/gkt1264
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Ontology (information science),Ontology,Data set,Biology,Expression (mathematics),Information repository,Bioinformatics,Computational biology,Genetics,Data model,DNA microarray,Gene expression profiling
Journal
42
Issue
ISSN
Citations 
D1
0305-1048
3
PageRank 
References 
Authors
0.48
18
9
Name
Order
Citations
PageRank
Harald Stachelscheid1192.53
Stefanie Seltmann2192.19
Fritz Lekschas3325.14
Jean-Fred Fontaine41699.23
Nancy Mah5181.60
Mariana Neves6312.60
Miguel A Andrade-Navarro722015.60
Ulf Leser82071174.23
Andreas Kurtz9303.42