Title
On the Way to Large-Scale and High-Resolution Brain-Chip Interfacing.
Abstract
Brain-chip-interfaces (BCHIs) are hybrid entities where chips and nerve cells establish a close physical interaction allowing the transfer of information in one or both directions. Typical examples are represented by multi-site-recording chips interfaced to cultured neurons, cultured/acute brain slices, or implanted “in vivo”. This paper provides an overview on recent achievements in our laboratory in the field of BCHIs leading to enhancement of signals transmission from nerve cells to chip or from chip to nerve cells with an emphasis on in vivo interfacing, either in terms of signal-to-noise ratio or of spatiotemporal resolution. Oxide-insulated chips featuring large-scale and high-resolution arrays of stimulation and recording elements are presented as a promising technology for high spatiotemporal resolution interfacing, as recently demonstrated by recordings obtained from hippocampal slices and brain cortex in implanted animals. Finally, we report on an automated tool for processing and analysis of acquired signals by BCHIs.
Year
DOI
Venue
2012
10.1007/s12559-011-9121-4
Cognitive Computation
Keywords
Field
DocType
Brain-chip interfacing,Electrolyte-oxide-semiconductor field effect transistors,Electrolyte-oxide-semiconductor capacitors,Multi transistor arrays,Multi electrode arrays,Local field potentials,Neuronal signal analysis
Cortex (botany),Biomedical engineering,Physical interaction,Pattern recognition,Computer science,Interfacing,Nerve cells,Chip,In vivo,Artificial intelligence,Local field potential,Hippocampal formation
Journal
Volume
Issue
ISSN
4
1
1866-9956
Citations 
PageRank 
References 
3
0.40
18
Authors
4
Name
Order
Citations
PageRank
Stefano Vassanelli15910.84
Mufti Mahmud28920.03
Stefano Girardi3163.35
Marta Maschietto473.02