Title
Comparing protein contact maps via Universal Similarity Metric: an improvement in the noise-tolerance.
Abstract
Comparing protein structures based on their contact maps similarity is an important problem in molecular biology. One motivation to seek fast algorithms for comparing contact maps is devising systems for reconstructing three-dimensional structure of proteins from their predicted contact maps. In this paper, we propose an algorithm to apply the Universal Similarity Metric (USM) to contact map comparison problem in a two-dimensional space. The major advantage of this algorithm is the highly improved noise-tolerance of the metric in comparison with its previous one-dimensional implementations. This is the first successful attempt to apply the USM to two-dimensional objects, without reducing their dimensionality.
Year
DOI
Venue
2009
10.1504/IJCBDD.2009.028821
I. J. Computational Biology and Drug Design
Keywords
Field
DocType
mutual information,molecular biology,bioinformatics
Protein structure comparison,Curse of dimensionality,Artificial intelligence,Mutual information,Bioinformatics,Noise tolerance,Machine learning,Mathematics
Journal
Volume
Issue
ISSN
2
2
1756-0756
Citations 
PageRank 
References 
2
0.38
10
Authors
2
Name
Order
Citations
PageRank
Sara Rahmati120.72
Janice I. Glasgow2392127.97