Title
Contrast-Independent Liver-Fat Quantification from Spectral CT Exams.
Abstract
The diagnosis and treatment of fatty liver disease requires accurate quantification of the amount of fat in the liver. Image-based methods for quantification of liver fat are of increasing interest due to the high sampling error and invasiveness associated with liver biopsy, which despite these difficulties remains the gold standard. Current computed tomography (CT) methods for liver-fat quantification are only semi-quantitative and infer the concentration of liver fat heuristically. Furthermore, these techniques are only applicable to images acquired without the use of contrast agent, even though contrast-enhanced CT imaging is more prevalent in clinical practice. In this paper, we introduce a method that allows for direct quantification of liver fat for both contrast-free and contrast-enhanced CT images. Phantom and patient data are used for validation, and we conclude that our algorithm allows for highly accurate and repeatable quantification of liver fat for spectral CT.
Year
DOI
Venue
2013
10.1007/978-3-642-40811-3_41
Lecture Notes in Computer Science
Field
DocType
Volume
Nuclear medicine,Pattern recognition,Sampling error,Computer science,Liver biopsy,Imaging phantom,Clinical Practice,Fatty liver,Computed tomography,Artificial intelligence
Conference
8149
Issue
ISSN
Citations 
Pt 1
0302-9743
0
PageRank 
References 
Authors
0.34
1
6
Name
Order
Citations
PageRank
Paulo R. S. Mendonça161050.38
Peter Lamb2204.33
András Kriston351.26
Kosuke Sasaki400.34
Masayuki Kudo500.34
Dushyant V Sahani6232.81