Title
Cell Nuclei Detection Using Globally Optimal Active Contours with Shape Prior.
Abstract
Cell nuclei detection in fluorescent microscopic images is an important and time consuming task for a wide range of biological applications. Blur, clutter, bleed through and partial occlusion of nuclei make this a challenging task for automated detection of individual nuclei using image analysis. This paper proposes a novel and robust detection method based on the active contour framework. The method exploits prior knowledge of the nucleus shape in order to better detect individual nuclei. The method is formulated as the optimization of a convex energy function. The proposed method shows accurate detection results even for clusters of nuclei where state of the art methods fail.
Year
DOI
Venue
2012
10.1007/978-3-642-33191-6_12
ADVANCES IN VISUAL COMPUTING, ISVC 2012, PT II
Keywords
Field
DocType
microscopy,image analysis,tracking,segmentation
Active contour model,Computer vision,Nucleus,Pattern recognition,Clutter,Segmentation,Computer science,Regular polygon,Software,Artificial intelligence
Conference
Volume
ISSN
Citations 
7432
0302-9743
1
PageRank 
References 
Authors
0.37
11
6
Name
Order
Citations
PageRank
Jonas De Vylder1147.62
Jan Aelterman28011.46
Mado Vandewoestyne310.37
Trees Lepez410.37
Dieter Deforce5142.56
Wilfried Philips61476124.85