Title
HiBrowse: multi-purpose statistical analysis of genome-wide chromatin 3D organization.
Abstract
Recently developed methods that couple next-generation sequencing with chromosome conformation capture-based techniques, such as Hi-C and ChIA-PET, allow for characterization of genome-wide chromatin 3D structure. Understanding the organization of chromatin in three dimensions is a crucial next step in the unraveling of global gene regulation, and methods for analyzing such data are needed. We have developed HiBrowse, a user-friendly web-tool consisting of a range of hypothesis-based and descriptive statistics, using realistic assumptions in null-models.
Year
DOI
Venue
2014
10.1093/bioinformatics/btu082
BIOINFORMATICS
Keywords
Field
DocType
genomics,genome,chromatin
Genome,Descriptive statistics,Source code,Computer science,Genomics,Software,Bioinformatics,Chromatin,Python (programming language),Chromosome conformation capture
Journal
Volume
Issue
ISSN
30
11
1367-4803
Citations 
PageRank 
References 
10
0.88
5
Authors
6
Name
Order
Citations
PageRank
Jonas Paulsen1152.03
Geir K Sandve223618.27
Sveinung Gundersen3293.11
Tonje G Lien4101.21
Kai Trengereid5131.63
Eivind Hovig621521.79