Paper Info
Title
Alternative Splicing in the Fly and the Worm: Splicing Databases for Drosophila melanogaster and Caenorhabditis elegans
Abstract
Alternative splicing is a widespread cellular phenomenon, which regulates gene expression in eukaryotic genomes. Availability of accumulating transcript and genomic sequence data has lead to generation of a wide-range of alternative splicing databases. Generally the available databases focus on mammalian transcriptomes. Here, we present two new alternative splicing databases for the model organisms, Drosophila melanogaster and Caenorhabditis elengans. Databases presented here allow the end-users to perform in-depth analysis of the alternative splicing events for their gene of interest. Utility of our databases are illustrated by presenting the extensively alternatively spliced DSCAM gene from Drosophila melanogaster and alternative splicing of the splicing regulatory factors U2AF, rsp-7 and swp-1 of Caenorhabditis elengans. In addition, using these two new splicing databases, we show that the majority of alternative splicing in both genomes is due to cassette exons.
Year
DOI
Venue
2011
10.1109/DEXA.2011.10
DEXA Workshops
Keywords
Field
DocType
alternative splicing databases,new splicing databases,alternative splicing event,available databases,splicing regulatory factor,dscam gene,alternative splicing,drosophila melanogaster,caenorhabditis elegans,new alternative,caenorhabditis elengans,splicing databases,databases,genetics,gene expression,genome sequence,database management systems,bioinformatics,genomics,splicing
Genome,Gene,Computer science,Exon,Alternative splicing,Caenorhabditis elegans,RNA splicing,Drosophila melanogaster,Caenorhabditis,Database
Conference
Citations 
PageRank 
References 
0
0.34
7
Authors
4
Name
Order
Citations
PageRank
Bahar Taneri1433.57
Ben Snyder2111.88
Alexey Novoradovsky330.88
Terry Gaasterland4447148.59