Title
MINT: Mutual Information based Transductive Feature Selection for Genetic Trait Prediction
Abstract
Whole genome prediction of complex phenotypic traits using high-density genotyping arrays has attracted a lot of attention, as it is relevant to the fields of plant and animal breeding and genetic epidemiology. Since the number of genotypes is generally much bigger than the number of samples, predictive models suffer from the curse of dimensionality. The curse of dimensionality problem not only affects the computational efficiency of a particular genomic selection method, but can also lead to a poor performance, mainly due to possible overfitting, or un-informative features. In this work, we propose a novel transductive feature selection method, called MINT, which is based on the MRMR (Max-Relevance and Min-Redundancy) criterion. We apply MINT on genetic trait prediction problems and show that, in general, MINT is a better feature selection method than the state-ofthe- art inductive method mRMR.
Year
DOI
Venue
2013
10.1109/TCBB.2015.2448071
IEEE/ACM Trans. Comput. Biology Bioinform.
Keywords
Field
DocType
feature selection,genetic trait prediction,mutual information,transductive
Transduction (machine learning),Feature selection,Trait,Computer science,Artificial intelligence,Overfitting,Phenotypic trait,Pattern recognition,Curse of dimensionality,Minimum redundancy feature selection,Mutual information,Bioinformatics,Machine learning
Journal
Volume
Issue
ISSN
13
3
1545-5963
Citations 
PageRank 
References 
5
0.51
6
Authors
6
Name
Order
Citations
PageRank
Dan He113312.54
irina rish291281.78
David Haws3393.82
Simon Teyssedre450.51
Zivan Karaman5103.26
Laxmi Parida677377.21