Title
Combination of radiological and gray level co-occurrence matrix textural features used to distinguish solitary pulmonary nodules by computed tomography.
Abstract
The objective of this study was to investigate the method of the combination of radiological and textural features for the differentiation of malignant from benign solitary pulmonary nodules by computed tomography. Features including 13 gray level co-occurrence matrix textural features and 12 radiological features were extracted from 2,117 CT slices, which came from 202 (116 malignant and 86 benign) patients. Lasso-type regularization to a nonlinear regression model was applied to select predictive features and a BP artificial neural network was used to build the diagnostic model. Eight radiological and two textural features were obtained after the Lasso-type regularization procedure. Twelve radiological features alone could reach an area under the ROC curve (AUC) of 0.84 in differentiating between malignant and benign lesions. The 10 selected characters improved the AUC to 0.91. The evaluation results showed that the method of selecting radiological and textural features appears to yield more effective in the distinction of malignant from benign solitary pulmonary nodules by computed tomography.
Year
DOI
Venue
2013
10.1007/s10278-012-9547-6
J. Digital Imaging
Keywords
Field
DocType
bp neural network,textural features,radiological features,solitary pulmonary nodules,feature selection
Nuclear medicine,Solitary pulmonary nodule,Co-occurrence matrix,Gray level,Computed tomography,Radiology,Area under the roc curve,Medicine,Radiological weapon
Journal
Volume
Issue
ISSN
26
4
1618-727X
Citations 
PageRank 
References 
9
0.60
13
Authors
10
Name
Order
Citations
PageRank
Haifeng Wu190.60
Tao Sun216816.47
Jingjing Wang390.93
Xia Li491.27
Wei Wang57122746.33
Da Huo6295.06
Pingxin Lv7251.46
Wen He890.60
Keyang Wang990.60
Xiuhua Guo10273.21