Name
Abstract | ||
|---|---|---|
This paper presents a tract-oriented analysis of diffusion tensor (DT) images of the human brain. We demonstrate that unlike the commonly used ROI-based methods for population studies, our technique is sensitive to the local variation of diffusivity parameters along the fiber tracts. We show the strength of the proposed approach in identifying the differences in schizophrenic data compared to controls. Statistically significant drops in fractional anisotropy are observed along the genu and bilaterally in the splenium, as well as an increase in principal eigenvalue in uncinate fasciculus. This is the first tract-oriented clinical study in which an anatomical atlas is used to guide the algorithm. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1007/978-3-540-85988-8_109 | MICCAI |
Keywords | Field | DocType |
statistically significant drop,anatomical atlas,diffusivity parameter,diffusion tensor,fractional anisotropy,tract-oriented dt-mri analysis,tract-oriented analysis,roi-based method,fiber tract,human brain,tract-oriented clinical study,population study,schizophrenia,artificial intelligence,statistical significance,algorithms | Population,Diffusion MRI,Computer science,Artificial intelligence,Clinical study,Pathology,Pattern recognition,Fractional anisotropy,Human brain,Uncinate fasciculus,Nuclear magnetic resonance,Schizophrenia,Splenium | Conference |
Volume | Issue | ISSN |
11 | Pt 1 | 0302-9743 |
Citations | PageRank | References |
2 | 0.44 | 5 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Mahnaz Maddah | 1 | 184 | 12.60 |
| Marek Kubicki | 2 | 397 | 36.50 |
| William M. Wells III | 3 | 5267 | 833.10 |
| Carl-fredrik Westin | 4 | 2040 | 173.83 |
| Martha E. Shenton | 5 | 394 | 41.14 |
| W. E. L. Grimson | 6 | 11451 | 2002.95 |