Name
Title | ||
|---|---|---|
Design of Artificial Tubular Protein Structures in 3D Hexagonal Prism Lattice Under HP Model |
Abstract | ||
|---|---|---|
Abstract The inverse protein folding problem is that of designing an amino acid sequence which has a prescribed native protein fold. This problem arises in drug design where a particular structure is necessary to ensure proper protein-protein in- teractions. In this paper, we show that in the HP model of Dill on the 3D (hexagonal prism) lat- tice it is possible to solve this problem for a class of structures (tubular structures). We also show that the proteins for the simplest (but arbitrary large) members of our class of structures (con- sisting of one or two tubes) are stable, i.e., fold uniquely into the desired tubular structure. Keywords: inverse protein folding, HP model, protein |
Year | Venue | Keywords |
|---|---|---|
2007 | BIOCOMP | drug design,protein structure,protein folding,amino acid sequence |
Field | DocType | Citations |
Crystallography,Hexagonal prism,Lattice (order),Protein design,Materials science,Protein structure | Conference | 1 |
PageRank | References | Authors |
0.38 | 5 | 5 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Arvind Gupta | 1 | 201 | 24.37 |
| Mehdi Karimi | 2 | 112 | 7.56 |
| Alireza Hadj Khodabakhshi | 3 | 12 | 2.68 |
| Ján Maňuch | 4 | 109 | 18.31 |
| Arash Rafiey | 5 | 339 | 28.08 |