Title
FACT--a framework for the functional interpretation of high-throughput experiments.
Abstract
Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-points that need to be analyzed in parallel. It is usually a matter of extensive testing and unknown beforehand, which of the possible approaches for the functional analysis will be the most informative.To address this problem, we have developed the Flexible Annotation and Correlation Tool (FACT). FACT allows for detection of important patterns in large data sets by simplifying the integration of heterogeneous data sources and the subsequent application of different algorithms for statistical evaluation or visualization of the annotated data. The system is constantly extended to include additional annotation data and comparison methods.FACT serves as a highly flexible framework for the explorative analysis of large genomic and proteomic result sets. The program can be used online; open source code and supplementary information are available at http://www.factweb.de.
Year
DOI
Venue
2005
10.1186/1471-2105-6-161
BMC Bioinformatics
Keywords
Field
DocType
functional analysis,microarrays,high throughput,gene expression profiling,dna microarray,cluster analysis,systems integration,algorithms,computer simulation,bioinformatics
Data mining,Computer science,Software,Bioinformatics,Throughput,Gene expression profiling,DNA microarray,System integration
Journal
Volume
Issue
ISSN
6
1
1471-2105
Citations 
PageRank 
References 
26
0.65
15
Authors
6
Name
Order
Citations
PageRank
Felix Kokocinski139755.58
Nicolas Delhomme2322.31
Gunnar Wrobel3402.38
Lars Hummerich4260.65
Grischa Toedt5913.47
Peter Lichter6260.65