Title
On genome evolution with innovation
Abstract
We introduce and analyse a simple probabilistic model of genome evolution. It is based on three fundamental evolutionary events: gene duplication, loss and innovation, and it is called DLI model. The focus of the paper is around the size distribution of gene families. The formulas for equilibrium gene family sizes are derived showing that they follow a logarithmic distribution. We consider also a disjoint union of DLI models and we present the result of this study. Some empirical results for microbial genomes are presented.
Year
DOI
Venue
2006
10.1007/11821069_69
MFCS
Keywords
Field
DocType
empirical result,size distribution,simple probabilistic model,disjoint union,logarithmic distribution,gene family,genome evolution,fundamental evolutionary event,equilibrium gene family size,dli model,gene duplication,probabilistic model
Genome,Discrete mathematics,Evolutionary algorithm,Computer science,Algorithm,Genome evolution,Computational biology,Paralogous Gene,Gene duplication,Gene family,Disjoint union,Logarithmic distribution
Conference
Volume
ISSN
ISBN
4162
0302-9743
3-540-37791-3
Citations 
PageRank 
References 
2
0.48
4
Authors
2
Name
Order
Citations
PageRank
Damian Wójtowicz1104.40
Jerzy Tiuryn21210126.00