Title
Modelling spatial heterogeneity and macromolecular crowding with membrane systems
Abstract
In biological processes, intrinsic noise, spatial heterogeneity and molecular crowding deeply affect the system dynamics. The classic stochastic methods lack of the necessary features needed for the description of these phenomena. Membrane systems are a suitable framework to embed these characteristics; in particular, the variants of τ-DPP and Sτ -DPP allow the modelling and stochastic simulations of multivolume biochemical systems, in which diffusion and size of volumes and chemicals are taken into account improving the description of these biological systems. In this paper we show, by means of two models of reactiondiffusion and crowded systems, the correctness and accuracy of our simulation methods.
Year
DOI
Venue
2010
10.1007/978-3-642-18123-8_23
Int. Conf. on Membrane Computing
Keywords
Field
DocType
intrinsic noise,biological process,molecular crowding,spatial heterogeneity,multivolume biochemical system,macromolecular crowding,necessary feature,biological system,crowded system,stochastic simulation,classic stochastic method,membrane system,biological systems,system dynamics,reaction diffusion
Cellular automaton,Biological system,Simulation,Crowding,Computer science,Correctness,Spatial heterogeneity,System dynamics,Macromolecular crowding,Distributed computing
Conference
Volume
ISSN
ISBN
6501
0302-9743
3-642-18122-8
Citations 
PageRank 
References 
6
0.68
8
Authors
5
Name
Order
Citations
PageRank
Ettore Mosca111911.01
Paolo Cazzaniga223527.16
Dario Pescini327425.92
Giancarlo Mauri42106297.38
Luciano Milanesi582387.40