Paper Info
Title
PhenoMiner: quantitative phenotype curation at the rat genome database.
Abstract
The Rat Genome Database (RGD) is the premier repository of rat genomic and genetic data and currently houses >40 000 rat gene records as well as human and mouse orthologs, >2000 rat and 1900 human quantitative trait loci (QTLs) records and >2900 rat strain records. Biological information curated for these data objects includes disease associations, phenotypes, pathways, molecular functions, biological processes and cellular components. Recently, a project was initiated at RGD to incorporate quantitative phenotype data for rat strains, in addition to the currently existing qualitative phenotype data for rat strains, QTLs and genes. A specialized curation tool was designed to generate manual annotations with up to six different ontologies/vocabularies used simultaneously to describe a single experimental value from the literature. Concurrently, three of those ontologies needed extensive addition of new terms to move the curation forward. The curation interface development, as well as ontology development, was an ongoing process during the early stages of the PhenoMiner curation project.
Year
DOI
Venue
2013
10.1093/database/bat015
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
Keywords
Field
DocType
data mining,genome,phenotype,workflow
Genome,Ontology (information science),Rat Genome Database,Data mining,Quantitative trait locus,Gene,Phenotype,Biology,Data objects,Bioinformatics,Molecular Sequence Annotation
Journal
Volume
ISSN
Citations 
2013
1758-0463
7
PageRank 
References 
Authors
0.80
7
11
Name
Order
Citations
PageRank
Stanley J. F. Laulederkind115015.81
Wei-Song Liu2545.58
Jennifer R. Smith313218.16
G. Thomas Hayman413213.77
Shur-Jen Wang513813.80
Rajni Nigam616926.98
Victoria Petri713317.76
Timothy Lowry8728.88
Jeff de Pons9839.84
Melinda R Dwinell1012517.82
Mary Shimoyama1120035.46