Title
Probabilistic Diffeomorphic Registration: Representing Uncertainty.
Abstract
This paper presents a novel mathematical framework for representing uncertainty in large deformation diffeomorphic image registration. The Bayesian posterior distribution over the deformations aligning a moving and a fixed image is approximated via a variational formulation. A stochastic differential equation (SDE) modeling the deformations as the evolution of a time-varying velocity field leads to a prior density over deformations in the form of a Gaussian process. This permits estimating the full posterior distribution in order to represent uncertainty, in contrast to methods in which the posterior is approximated via Monte Carlo sampling or maximized in maximum a-posteriori (MAP) estimation. The framework is demonstrated in the case of landmark-based image registration, including simulated data and annotated pre and intra-operative 3D images.
Year
DOI
Venue
2014
10.1007/978-3-319-08554-8_8
BIOMEDICAL IMAGE REGISTRATION (WBIR 2014)
Field
DocType
Volume
Computer vision,Mathematical optimization,Monte Carlo method,Computer science,Vector field,Stochastic differential equation,Posterior probability,Artificial intelligence,Gaussian process,Probabilistic logic,Image registration,Bayesian probability
Conference
8545
ISSN
Citations 
PageRank 
0302-9743
1
0.35
References 
Authors
7
4
Name
Order
Citations
PageRank
Demian Wassermann17611.03
Matthew Toews224720.60
Marc Niethammer373168.16
William M. Wells III45267833.10