Title
Probik: Protein Backbone Motion by Inverse Kinematics.
Abstract
To investigate the parameters of the protein design problem that we are exploring in collaboration with biochemists, we developed a tool that uses inverse kinematics to support moving small fragments of protein backbone, while respecting biochemists' desires to "remain in favorable regions of the Ramachandran plot" and "preserve ideal geometry." By presenting estimates of derivatives in response to motion, we are able to refine these qualitative desires as we work with our collaborators. We then explore low dimensional bases to parameterize the space of backbone motions.
Year
DOI
Venue
2005
10.1007/10991541_26
ALGORITHMIC FOUNDATIONS OF ROBOTICS VI
Keywords
DocType
Volume
protein design,backbone geometry,six revolute joint manipulator,Denavit-Hartenberg frames
Journal
17
Issue
ISSN
Citations 
11
1610-7438
4
PageRank 
References 
Authors
0.47
9
3
Name
Order
Citations
PageRank
Kimberly Noonan140.47
David O'Brien240.47
Jack Snoeyink32842231.68