Title
Dynamic querying for pattern identification in microarray and genomic data
Abstract
Data sets involving linear ordered sequences are a recurring theme in bioinformatics. Dynamic query tools that support exploration of these data sets can be useful for identifying patterns of interest. This paper describes the use of one such tool - timesearcher - to interactively explore linear sequence data sets taken from two bioinformatics problems. Microarray time course data sets involve expression levels for large numbers of genes over multiple time points. Timesearcher can be used to interactively search these data sets for genes with expression profiles of interest. The occurrence frequencies of short sequences of DNA in aligned exons can be used to identify sequences that play a role in the pre-mRNA splicing. Timesearcher can be used to search these data sets for candidate splicing signals.
Year
DOI
Venue
2003
10.1109/ICME.2003.1221346
ICME
Keywords
Field
DocType
genes,expression level,multiple time point,pattern recognition,dynamic query tool,data sets,genetics,timesearcher,splicing,genomic data,medical signal processing,expression profiles,large number,sequences,macromolecules,premrna splicing,linear sequence data,dynamic querying,microarray time course data,microarray,pre-mrna splicing,bioinformatics problem,linear ordered sequences,bioinformatics,expression profile,pattern identification,query processing,signal processing,technical report,displays,gene expression,linear order,genomics,frequency
Data mining,Data set,Microarray,Computer science,Genomics,Data sequences,RNA splicing,Pattern identification,Dynamic query
Conference
Volume
ISBN
Citations 
3
0-7803-7965-9
15
PageRank 
References 
Authors
1.74
4
4
Name
Order
Citations
PageRank
H. Hochheiser1151.74
E. H. Baehrecke2151.74
S. M. Mount3151.74
Ben Shneiderman4127723081.95