Name
Title | ||
|---|---|---|
Validation of Cone-Beam CT Measurements of Tumour Burden Using Three-Dimensional Histopathology: Initial Results For a Lumpectomy |
Abstract | ||
|---|---|---|
Tumour size is an important prognostic indicator in breast cancer. This is typically measured as a simple linear diameter, although tumour volume may be a better surrogate of tumour burden. We have been optimizing techniques for three-dimensional histopathology based on digital scanning light microscopy of whole-mount, whole-specimen serial sections. We apply this to validate tumour volume measurements obtained using specimen cone-beam CT imaging. We demonstrate initial results for this technique using one lumpectomy and then show examples of how this technique can serve as a `gateway' to validating emerging functional and molecular imaging modalities. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1007/978-3-540-70538-3_61 | Digital Mammography / IWDM |
Keywords | Field | DocType |
cone-beam ct measurements,initial results,three-dimensional histopathology,important prognostic indicator,tumour size,tumour volume measurement,tumour volume,breast cancer,molecular imaging modality,specimen cone-beam ct imaging,initial result,tumour burden,better surrogate,light microscopy,molecular imaging,three dimensional | Lumpectomy,Molecular imaging,Cupric sulphate,Breast cancer,Tumour volume,Histopathology,Radiology,Microscopy,Materials science | Conference |
Volume | ISSN | Citations |
5116 | 0302-9743 | 1 |
PageRank | References | Authors |
0.54 | 3 | 9 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| G. M. Clarke | 1 | 1 | 0.54 |
| James G. Mainprize | 2 | 14 | 9.82 |
| Chris Peressotti | 3 | 4 | 1.34 |
| L. Sun | 4 | 1 | 0.54 |
| D. Wang | 5 | 1 | 0.54 |
| J. T. Zubovits | 6 | 1 | 0.54 |
| C. M. Holloway | 7 | 1 | 0.54 |
| G. J. Czarnota | 8 | 3 | 1.62 |
| M. J. Yaffe | 9 | 1 | 0.54 |