Title
A three-stage expert system based on support vector machines for thyroid disease diagnosis.
Abstract
In this paper, we present a three-stage expert system based on a hybrid support vector machines (SVM) approach to diagnose thyroid disease. Focusing on feature selection, the first stage aims at constructing diverse feature subsets with different discriminative capability. Switching from feature selection to model construction, in the second stage, the obtained feature subsets are fed into the designed SVM classifier for training an optimal predictor model whose parameters are optimized by particle swarm optimization (PSO). Finally, the obtained optimal SVM model proceeds to perform the thyroid disease diagnosis tasks using the most discriminative feature subset and the optimal parameters. The effectiveness of the proposed expert system (FS-PSO-SVM) has been rigorously evaluated against the thyroid disease dataset, which is commonly used among researchers who use machine learning methods for thyroid disease diagnosis. The proposed system has been compared with two other related methods including the SVM based on the Grid search technique (Grid-SVM) and the SVM based on Grid search and principle component analysis (PCA-Grid-SVM) in terms of their classification accuracy. Experimental results demonstrate that FS-PSO-SVM significantly outperforms the other ones. In addition, Compared to the existing methods in previous studies, the proposed system has achieved the highest classification accuracy reported so far by 10-fold cross-validation (CV) method, with the mean accuracy of 97.49% and with the maximum accuracy of 98.59%. Promisingly, the proposed FS-PSO-SVM expert system might serve as a new candidate of powerful tools for diagnosing thyroid disease with excellent performance.
Year
DOI
Venue
2012
10.1007/s10916-011-9655-8
J. Medical Systems
Keywords
Field
DocType
discriminative feature subset,thyroid disease diagnosis,thyroid disease diagnosis.support.vector machines.expert system.fisher score.particle swarm optimization,feature subsets,svm classifier,optimal svm model proceed,proposed system,three-stage expert system,proposed expert system,feature selection,proposed fs-pso-svm expert system,diverse feature subsets,support vector machines,thyroid disease
Data mining,Feature selection,Artificial intelligence,Medicine,Discriminative model,Particle swarm optimization,Hyperparameter optimization,Pattern recognition,Scoring algorithm,Expert system,Support vector machine,Machine learning,Principal component analysis
Journal
Volume
Issue
ISSN
36
3
0148-5598
Citations 
PageRank 
References 
18
0.77
18
Authors
6
Name
Order
Citations
PageRank
Hui-Ling Chen165526.09
Bo Yang282264.08
Gang Wang322313.31
Jie Liu419922.56
Yi-Dong Chen5180.77
Dayou Liu681468.17