Name
Title | ||
|---|---|---|
Manipulating brain connectivity with δ9-tetrahydrocannabinol: A pharmacological resting state FMRI study. |
Abstract | ||
|---|---|---|
Resting state-functional magnetic resonance imaging (RS-FMRI) is a neuroimaging technique that allows repeated assessments of functional connectivity in resting state. While task-related FMRI is limited to indirectly measured drug effects in areas affected by the task, resting state can show direct CNS effects across all brain networks. Hence, RS-FMRI could be an objective measure for compounds affecting the CNS. Several studies on the effects of cannabinoid receptor type 1 (CB1)-receptor agonist δ9-tetrahydrocannabinol (THC) on task-dependent FMRI have been performed. However, no studies on the effects of cannabinoids on resting state networks using RS-FMRI have been published. Therefore, we investigated the effects of THC on functional brain connectivity using RS-FMRI. |
Year | DOI | Venue |
|---|---|---|
2012 | 10.1016/j.neuroimage.2012.07.051 | NeuroImage |
Keywords | DocType | Volume |
Resting state FMRI,THC,Pharmacokinetics,Brain connectivity,CNS effects,Pharmacodynamics | Journal | 63 |
Issue | ISSN | Citations |
3 | 1053-8119 | 2 |
PageRank | References | Authors |
0.46 | 0 | 7 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Linda E. Klumpers | 1 | 2 | 0.80 |
| David M. Cole | 2 | 262 | 16.49 |
| Najmeh Khalili-Mahani | 3 | 47 | 6.02 |
| Roelof P. Soeter | 4 | 2 | 0.46 |
| Erik T. te Beek | 5 | 2 | 0.46 |
| serge a r b rombouts | 6 | 100 | 13.51 |
| Joop M. A. van Gerven | 7 | 13 | 2.53 |