Name
Abstract | ||
|---|---|---|
The mechanical function of soft collagenous tissues is inherently multiscale, with the tissue dimension being in the centimeter length scale and the underlying collagen network being in the micrometer length scale. This paper uses a volume averaging multiscale model to predict the collagen gel mechanics. The model is simulated using a multiscale component toolkit that is capable of dealing with any 3D geometries. Each scale in the multiscale model is treated as an independent component that exchanges the deformation and average stress information through a scale-linking operator. An arterial bifurcation was simulated using the multiscale model, and the results demonstrated that the mechanical response of the soft tissues is strongly sensitive to the network orientation and fiber-to-fiber interactions. |
Year | DOI | Venue |
|---|---|---|
2009 | 10.1007/s00366-008-0111-4 | Eng. Comput. (Lond.) |
Keywords | Field | DocType |
multiscale component toolkit,multiscale model,mechanical function,micrometer length scale,independent component,mechanical response,centimeter length scale,soft collagenous tissue,tissue engineeringmultiscale computation � volume averagingcollagen fiber,complex geometries,bioartificial soft tissue,multiscale computation,network orientation,collagen gel mechanic,soft tissue,tissue engineering,multiscale modeling,length scale | Mathematical optimization,Length scale,Biological system,Operator (computer programming),Deformation (mechanics),Soft tissue,Micrometer,Mathematics,Bifurcation,Computation | Journal |
Volume | Issue | ISSN |
25 | 1 | 1435-5663 |
Citations | PageRank | References |
1 | 0.35 | 3 |
Authors | ||
4 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Xiaojuan Luo | 1 | 68 | 6.91 |
| T. Stylianopoulos | 2 | 1 | 2.04 |
| Victor H. Barocas | 3 | 1 | 1.70 |
| Mark S. Shephard | 4 | 479 | 67.67 |