Paper Info
Title
Rnadb - A Comprehensive Mammalian Noncoding Rna Database
Abstract
In recent years, there have been increasing numbers of transcripts identified that do not encode proteins, many of which are developmentally regulated and appear to have regulatory functions. Here, we describe the construction of a comprehensive mammalian noncoding RNA database (RNAdb) which contains over 800 unique experimentally studied noncoding RNAs (ncRNAs), including many associated with diseases and/or developmental processes. The database is available at http://research.imb.uq. edu.au/RNAdb and is searchable by many criteria. It includes microRNAs and snoRNAs, but not infrastructural RNAs, such as rRNAs and tRNAs, which are catalogued elsewhere. The database also includes over 1100 putative antisense ncRNAs and almost 20000 putative ncRNAs identified in high-quality murine and human cDNA libraries, with more to be added in the near future. Many of these RNAs are large, and many are spliced, some alternatively. The database will be useful as a foundation for the emerging field of RNomics and the characterization of the roles of ncRNAs in mammalian gene expression and regulation.
Year
DOI
Venue
2005
10.1093/nar/gri089
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
pseudogenes,gene expression,human genome,micrornas,microrna,identification,cdna library,genes,chromosome 21,noncoding rna
Long non-coding RNA,Pseudogene,Gene,Biology,Small nucleolar RNA,microRNA,cDNA library,Human genome,Genetics,Non-coding RNA,Molecular biology,Database
Journal
Volume
Issue
ISSN
33
Database-Issue
0305-1048
Citations 
PageRank 
References 
13
2.94
7
Authors
9
Name
Order
Citations
PageRank
Ken C. Pang1699.59
Stuart Stephen2377.09
Pär Engström329223.69
Khairina Tajul-Arifin4163.74
Weisan Chen5132.94
Claes Wahlestedt6465.88
Boris Lenhard771656.46
Yoshihide Hayashizaki828631.47
John S. Mattick915917.77