Name
Abstract | ||
|---|---|---|
We combined measures of resting-state functional magnetic resonance imaging and diffusion tensor imaging (DTI) to investigate alterations of function-structure relationships in patients with early-onset schizophrenia. DTI analysis revealed reduced fractional anisotropy in right frontal white matter. Corresponding gray matter regions showed reduced functional connectivity with other regions in the brain in patients with early-onset schizophrenia, compared with healthy controls. Our results demonstrated abnormal function-structure relationships in early-onset schizophrenia, and supported the view that white matter lesions might disrupt the neural circuits between frontal regions and other brain regions, and affect the functional connectivity in the frontal cortex. |
Year | DOI | Venue |
|---|---|---|
2009 | 10.2991/ijcis.2009.2.4.6 | INTERNATIONAL JOURNAL OF COMPUTATIONAL INTELLIGENCE SYSTEMS |
Keywords | Field | DocType |
Functional connectivity, Anatomical connectivity, Resting fMRI, Fractional anisotropy, Early-onset schizophrenia | Diffusion MRI,Early onset schizophrenia,Neuroscience,Functional magnetic resonance imaging,Fractional anisotropy,Resting state fMRI,Artificial intelligence,Biological neural network,Schizophrenia,Mathematics,Hyperintensity,Machine learning | Journal |
Volume | Issue | ISSN |
2 | 4 | 1875-6891 |
Citations | PageRank | References |
0 | 0.34 | 6 |
Authors | ||
7 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Ming Ke | 1 | 3 | 2.26 |
| Hui Shen | 2 | 134 | 15.32 |
| Jintu Fan | 3 | 16 | 1.74 |
| Xing Huang | 4 | 0 | 0.34 |
| Zongtan Zhou | 5 | 412 | 33.89 |
| Xiaogang Chen | 6 | 184 | 25.18 |
| Dewen Hu | 7 | 1290 | 101.20 |