Name
Abstract | ||
|---|---|---|
This study reports a new microfluidic-based cell culture platform. Moreover, microheaters, a micro temperature sensor, micropumps were integrated into the system to achieve a self-contained device for standard perfusion mammalian cell culture. One of key features of the proposed platform is the design of ultra-thin cell culture chamber allowing real-time cellular and sub-cellular imaging. The entire cell culture process can be performed automatically without human intervention. The developed platform was used for study of drug delivery on oral cancer cells. Experimental data showed that it can successfully monitor the dividing process of cancer cells. Besides, the cell response to anti-cancer drugs was also investigated. The developed platform can be promising for cell-based study. |
Year | DOI | Venue |
|---|---|---|
2009 | 10.1109/NEMS.2009.5068564 | NEMS |
Keywords | Field | DocType |
subcellular imaging,oral cancer cells,self-contained device,cellular biophysics,drug delivery,biomems,microheaters,standard perfusion mammalian cell,microfluidic-based cell culture platform,haemorheology,cell imaging,microsensors,mems,proposed platform,micropumps,perfusion mammalian cell culture,entire cell culture process,ultrathin cell culture chamber,ultra-thin cell culture chamber,biomedical imaging,drug delivery systems,temperature microsensor,cell response,microfluidics,new microfluidic-based cell culture,developed platform,cell culture,oral cancer cell,cell-based study,cancer cell,real time,imaging,microchannel,real time systems,cancer,microscopy | Cell culture,Nanotechnology,Cellular biophysics,Cancer cell,Microfluidics,Entire cell,Cell,Drug delivery,Materials science | Conference |
ISSN | ISBN | Citations |
2474-3747 | 978-1-4244-4630-8 | 0 |
PageRank | References | Authors |
0.34 | 0 | 4 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Dar-Bin Shieh | 1 | 0 | 0.68 |
| Chia-Chun Hsieh | 2 | 0 | 0.34 |
| Song-Bin Huang | 3 | 9 | 3.97 |
| Gwo-Bin Lee | 4 | 7 | 16.66 |