Title
A Generic Grid Interface And Execution Framework For Biomedical Applications
Abstract
Nowadays, there is a growing demand for high computing power and large storage systems in the biomedical domain. Grid computing has recently gained a great deal of interest as an enabling technology towards realization of the e-Science vision, offering a highly flexible and controlled resource-sharing and collaborative environment. However, there is still a lack of user-friendly means to either access the Grid or enable the execution of existing biomedical software into Grid infrastructures. In this work, a generic interface enabling straightforward execution of biomedical applications to Grid infrastructures is presented, with respect to their input/output, software parameterization and attributes for compilation and execution, potentially external files used, etc. This functionality is supported by the definition of a generic XML schema for application description and, accordingly, by the construction of a dynamic graphical user interface based on this schema. Additionally, it provides the means to guide the user towards effective interaction with the Grid, in the entire lifecycle of application execution. The potential and applicability of the proposed approach, as well as the benefits of Grid computing, are illustrated via two existing biomedical applications, namely, the hyperparameter optimization of a Gaussian Support Vector Machine (SVM) classifier applied on human splice site prediction and the simulation of 2D cardiac propagation with the Luo-Rudy I model.
Year
DOI
Venue
2008
10.1109/BIBE.2008.4696817
8TH IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOENGINEERING, VOLS 1 AND 2
Keywords
Field
DocType
hyperparameter optimization,support vector machine,grid computing,computational modeling,input output,xml schema,xml,resource sharing,storage system,bioinformatics,graphical user interfaces,cardiology,support vector machines,construction industry,graphic user interface,groupware
Hyperparameter optimization,Grid computing,XML,Collaborative software,Computer science,Graphical user interface,XML schema,Artificial intelligence,Semantic grid,Bioinformatics,Machine learning,Grid
Conference
ISSN
Citations 
PageRank 
2471-7819
1
0.37
References 
Authors
9
5
Name
Order
Citations
PageRank
Konstantinos I. Vegoudakis110.71
Vassilis Koutkias224340.66
Andigoni Malousi3254.86
Ioanna Chouvarda415538.47
Nicos Maglaveras530654.35