Title
Evaluation of techniques for increasing recall in a dictionary approach to gene and protein name identification
Abstract
Gene and protein name identification in text requires a dictionary approach to relate synonyms to the same gene or protein, and to link names to external databases. However, existing dictionaries are incomplete. We investigate two complementary methods for automatic generation of a comprehensive dictionary: combination of information from existing gene and protein databases and rule-based generation of spelling variations. Both methods have been reported in literature before, but have hitherto not been combined and evaluated systematically. We combined gene and protein names from several existing databases of four different organisms. The combined dictionaries showed a substantial increase in recall on three different test sets, as compared to any single database. Application of 23 spelling variation rules to the combined dictionaries further increased recall. However, many rules appeared to have no effect and some appear to have a detrimental effect on precision.
Year
DOI
Venue
2007
10.1016/j.jbi.2006.09.002
Journal of Biomedical Informatics
Keywords
Field
DocType
dictionary,information extraction,rule based
Data mining,Gene,Information retrieval,Computer science,Synonym,Information extraction,Natural language processing,Artificial intelligence,Spelling,Protein Databases,Recall
Journal
Volume
Issue
ISSN
40
3
1532-0464
Citations 
PageRank 
References 
15
0.80
18
Authors
4
Name
Order
Citations
PageRank
Martijn J. Schuemie152934.40
Barend Mons243033.31
Marc Weeber345734.63
Jan A. Kors463537.25