Title
An agent- and ontology-based system for integrating public gene, protein, and disease databases.
Abstract
In this paper, we describe OntoFusion, a database integration system. This system has been designed to provide unified access to multiple, heterogeneous biological and medical data sources that are publicly available over Internet. Many of these databases do not offer a direct connection, and inquiries must be made via Web forms, returning results as HTML pages. A special module in the OntoFusion system is needed to integrate these public 'Web-based' databases. Domain ontologies are used to do this and provide database mapping and unification. We have used the system to integrate seven significant and widely used public biomedical databases: OMIM, PubMed, Enzyme, Prosite and Prosite documentation, PDB, SNP, and InterPro. A case study is detailed in depth, showing system performance. We analyze the system's architecture and methods and discuss its use as a tool for biomedical researchers.
Year
DOI
Venue
2007
10.1016/j.jbi.2006.02.014
Journal of Biomedical Informatics
Keywords
Field
DocType
prosite documentation,ontofusion system,biomedical informatics,heterogeneous databases,public gene,system performance,database integration system,disease databases,ontology-based system,case study,biomedical researcher,public biomedical databases,genomic databases,web form,html page,database mapping,bioinformatics,data integration,enzyme,database integration,data integrity
Ontology (information science),Data integration,Data mining,Information retrieval,Computer science,Data mapping,Database testing,Database theory,Documentation,PROSITE,Database,InterPro
Journal
Volume
Issue
ISSN
40
1
1532-0480
Citations 
PageRank 
References 
17
1.15
27
Authors
6
Name
Order
Citations
PageRank
Raúl Alonso-Calvo110714.64
V Maojo2896.65
H Billhardt3171.15
F Martin-Sanchez41007.62
Miguel García-Remesal512813.75
david perezrey613520.28